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Generic wellbutrin bupropion, naloxone hydrochloride and alprazolam ) ( Figure 2 C). Figure 2 View largeDownload slide Clinical pharmacology of bupropion and alprazolam in patients with bipolar depression. Citalopram (20 mg) and escitalopram (100 were given orally to patients with treatment-resistant bipolar depression. The drugs were given at bedtime in addition to their usual treatment Finasteride generic online plan, which included an antidepressant, lithium, antipsychotic medication, or a mood stabilizer. Discussion Our patients were not resistant to bupropion, but all appeared be at very low risk for suicide and had low risk factors for suicidal behavior. Nevertheless, they all developed acute mania on hi